专利名称 | Salt and polymorph of pyrazolopyrimidinone compound, and pharmaceutical composition containing the same, preparation method and use thereof | 申请号 | US201214238790 | 专利类型 | US | 公开(公告)号 | US9527849(B2) | 公开(授权)日 | 2016.12.27 | 申请(专利权)人 | 中国科学院上海药物研究所 | 发明(设计)人 | Li Jianfeng;Tian Guanghui;Wang Zhen;Suo Jin;Jiang Xiangrui;Liu Zheng;Yang Xiaojun;Xie Zhu;Zhao Xianguo;Zhu Weiliang;Jiang Hualiang;Shen Jingshan | 主分类号 | C07D487/04 | IPC主分类号 | C07D487/04;A61K31/519;A61P15/10;A61P13/10;A61P9/10;A61P9/04;A61P13/12;A61P11/06;A61P29/00;A61P27/06;A61P9/12 | 专利有效期 | Salt and polymorph of pyrazolopyrimidinone compound, and pharmaceutical composition containing the same, preparation method and use thereof 至Salt and polymorph of pyrazolopyrimidinone compound, and pharmaceutical composition containing the same, preparation method and use thereof | 法律状态 | 说明书摘要 | The present invention relates to new salts of pyrazolopyrimidinone represented by formula (I), and pharmaceutically acceptable polymorph, solvate, hydrate, dehydrate, co-crystallization, anhydrous, or amorphous form thereof, the pharmaceutical compositions, and a pharmaceutical unit dosage form containing the same, wherein x represents organic or inorganic acids, preferable maleic acid, succinic acid, methanesulfonic acid, hydrochloric acid, etc. The invention further relates to co-crystals or complexes of compounds of pyrazolopyrimidinone and pharmaceutical compositions containing the same. The present invention also relates to a process for the preparation, use thereof and pharmaceutical preparation containing the salts or crystalline forms.; |
1、源头对接,价格透明
2、平台验证,实名审核
3、合同监控,代办手续
4、专员跟进,交易保障