Marine streptomyces, pyranosesquiterpene compound, as well as preparation method and applications thereof

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专利名称 Marine streptomyces, pyranosesquiterpene compound, as well as preparation method and applications thereof 申请号 US201213885853 专利类型 US 公开(公告)号 US9200301(B2) 公开(授权)日 2015.12.01 申请(专利权)人 中国科学院南海海洋研究所 发明(设计)人 Long Lijuan;Tian Xinpeng;Li Jie;Luo Xiongming;Qi Zhenxiong;Yin Tuan;Yin Hao;Yang Jian 主分类号 C12P17/06 IPC主分类号 C12P17/06;C12R1/465;A01N43/16;C12N1/20;C07D309/32;A01N43/90;A01N63/00;A01N63/02 专利有效期 Marine streptomyces, pyranosesquiterpene compound, as well as preparation method and applications thereof 至Marine streptomyces, pyranosesquiterpene compound, as well as preparation method and applications thereof 法律状态 说明书摘要 The invention discloses marine Streptomyces sp., a Pyranosesquiterpene compound, as well as a preparation method and uses thereof. Streptomyces sp. SCSIO 01689 was collected in China Center for Type Culture Collection (CCTCC) (Address: Wuhan University, Wuhan City, China) with the collection number of CCTCC NO: M 2011257 on Jul. 18, 2011. The Streptomyces sp. SCSIO 01689 can produce the Pyranosesquiterpene compound with better anti-Escherichia coli activity and anti-Artemia activity, as well as Cyclo(D)-Pro-(D)-Ile, Cyclo(D)-Pro-(D)-Leu and Cyclo(D)-trans-4-OH-Pro-(D)-Phe with better anti-Vibrio anguillarum activity and anti-Artemia activity, thereby providing a new way for preparing the Cyclo(D)-Pro-(D)-Ile, the Cyclo(D)-Pro-(D)-Leu and the Cyclo(D)-trans-4-OH-Pro-(D)-Phe. The Pyranosesquiterpene compound can be used for preparing anti-Escherichia coli medicaments and anti-Artemia medicaments, as well as preparing condiments as a condiment precursor compound.

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