| 专利名称 | Substituted [1,2,4]triazolo[4,3-a]pyrazines as PARP-1 inhibitors | 申请号 | US201314418705 | 专利类型 | US | 公开（公告）号 | US9255106(B2) | 公开（授权）日 | 2016.02.09 | 申请（专利权）人 | 中国科学院上海药物研究所 | 发明（设计）人 | Zhang Ao;Miao Zehong;Ye Na;Huan Xiajuan;Song Zilan;Chen Chuanhuizi;Chen Yi;Ding Jian | 主分类号 | A61K31/4985 | IPC主分类号 | A61K31/4985;C07D241/38;C07D487/04;A61K31/501;A61K31/502 | 专利有效期 | Substituted [1,2,4]triazolo[4,3-a]pyrazines as PARP-1 inhibitors 至Substituted [1,2,4]triazolo[4,3-a]pyrazines as PARP-1 inhibitors | 法律状态 | 说明书摘要 | Provided is a piperazinotriazole compound represented by general formula I or a pharmaceutically acceptable salt, stereoisomer, tautomer or hydrate thereof. Also provided are a pharmaceutical composition comprising the compound, a method for preparing the compound and a method of use thereof as a high-selectivity poly(adenosine diphosphate-ribose)polymerase-1 (PARP-1) inhibitor in the preparation of drugs for the prevention and/or treatment of PARP-related diseases.; |
1、源头对接，价格透明
2、平台验证，实名审核
3、合同监控，代办手续
4、专员跟进，交易保障