ALPHA-AMINO-N-SUBSTITUTED AMIDES, PHARMACEUTICAL COMPOSITION CONTAINING THEM AND USES THEREOF

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专利名称 ALPHA-AMINO-N-SUBSTITUTED AMIDES, PHARMACEUTICAL COMPOSITION CONTAINING THEM AND USES THEREOF 申请号 EP20080858616 专利类型 EP 公开(公告)号 EP2233467(B1) 公开(授权)日 2012.09.19 申请(专利权)人 中国科学院上海药物研究所 发明(设计)人 NAN, FAJUN;LI, JIA;DING, JIAN;LIU, GANG;XIE, CHUANMING;MIAO, ZEHONG;TAI, WANYI 主分类号 C07C237/16 IPC主分类号 C07C237/16;A61K31/16;A61P35/00;C07C233/05;C07C233/09;C07C233/18;C07C233/20 专利有效期 ALPHA-AMINO-N-SUBSTITUTED AMIDES, PHARMACEUTICAL COMPOSITION CONTAINING THEM AND USES THEREOF 至ALPHA-AMINO-N-SUBSTITUTED AMIDES, PHARMACEUTICAL COMPOSITION CONTAINING THEM AND USES THEREOF 法律状态 说明书摘要 The present invention relates to filed of pharmaceutical chemistry. Disclosed are a series of ±-amino-N-substituted amide compounds having a structure of the following formula, the pharmaceutically acceptable salts thereof, and the pharmaceutical composition comprising the same. The ±-amino-N-substituted amide compounds or the pharmaceutically acceptable salts thereof according to the present invention have anti-tumor and/or anti-cancer activities in vivo and in vitro, can effectively depress the growth of various tumor cells and/or cancer cells, and thus can be used in preparing drugs for treating tumors and/or cancers.

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