| 专利名称 | 13,13A-DIHYDROBERBERINE DERIVATIVES, THEIR PHARMACEUTICAL COMPOSITION AND USE | 申请号 | EP20070816496 | 专利类型 | EP | 公开（公告）号 | EP2070926(B1) | 公开（授权）日 | 2011.09.07 | 申请（专利权）人 | 中国科学院上海药物研究所 | 发明（设计）人 | HU, LIHONG;YE, JIMING;LI, JINGYA;JAMES, DAVID, E;KRAEGEN, EDWARD, W;ZHANG, HANKUN;CHENG, ZHE;LI, JIA | 主分类号 | C07D455/03 | IPC主分类号 | C07D455/03;A61K31/4375;A61P3/04;A61P3/06;A61P3/10 | 专利有效期 | 13,13A-DIHYDROBERBERINE DERIVATIVES, THEIR PHARMACEUTICAL COMPOSITION AND USE 至13,13A-DIHYDROBERBERINE DERIVATIVES, THEIR PHARMACEUTICAL COMPOSITION AND USE | 法律状态 | 说明书摘要 | The present invention provides 13,13a-dihydroberberine derivatives or their physiologically acceptable salts represented by the following formula, pharmaceutical compositions comprising the same, and uses thereof. The 13,13a-dihydroberberine derivatives have an activity of promoting glucose absorption in muscle cells, and the whole animal tests show that the present compounds have effects on improving glucose-tolerance and insulin-resistance, facilitating weight loss, relieving fatty liver and the like. Thus, the present compounds can be used in treating diabetes mellitus, adiposity, fatty liver and complications thereof induced by insulin resistance. |
1、源头对接，价格透明
2、平台验证，实名审核
3、合同监控，代办手续
4、专员跟进，交易保障