| 专利名称 | Method for preparing optically pure (?)-clausenamide compound | 申请号 | US201114125055 | 专利类型 | US | 公开（公告）号 | US8912345(B2) | 公开（授权）日 | 2014.12.16 | 申请（专利权）人 | 中国科学院化学研究所 | 发明（设计）人 | Shi Yian;Peng Xianyou;Li Peijun | 主分类号 | C07D207/273 | IPC主分类号 | C07D207/273 | 专利有效期 | Method for preparing optically pure (?)-clausenamide compound 至Method for preparing optically pure (?)-clausenamide compound | 法律状态 | 说明书摘要 | Disclosed in the present invention is a method for preparing a (?)-clausenamide compound of formula (I), comprising: firstly, catalyzing the asymmetrical epoxidation of trans-cinnamate using a chiral ketone derived from fructose or a hydrate thereof as a catalyst, and then subjecting the product to amidation, oxidation, cyclization and reduction successively to finally obtain the optically pure (?)-clausenamide compound of formula (I). |
1、源头对接，价格透明
2、平台验证，实名审核
3、合同监控，代办手续
4、专员跟进，交易保障