Use of 9, 10-anthraquinone compounds

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专利名称 Use of 9, 10-anthraquinone compounds 申请号 US200913130130 专利类型 US 公开(公告)号 US8895725(B2) 公开(授权)日 2014.11.25 申请(专利权)人 中国科学院上海巴斯德研究所 发明(设计)人 Wang Shuguang;Zhong Jin;Kong Deyun;Hu Jue;Li Bo;Gao Wen;Gai Chunyan;Zhuang Changlong;Mao Haitao 主分类号 A61K31/192 IPC主分类号 A61K31/192;C09B1/473;A61K36/708;A61K36/74;A61K31/185;A61K31/704;A61K31/122;A61K31/7004;A61K36/482 专利有效期 Use of 9, 10-anthraquinone compounds 至Use of 9, 10-anthraquinone compounds 法律状态 说明书摘要 Use of 9,10-anthraquinone compounds of formula (I) or pharmaceutical salts thereof or plant extracts containing said compounds in the preparation of anti-HCV medicaments is disclosed, in which Y1 are Y2 are independently hydrogen, hydroxyl or groups of formula (II); and R1, R2, R3, R4, R5 and R6 are independently hydrogen, hydroxyl, carboxyl, cyano group, nitro group, groups of formula (III) or groups selected from those substituted or unsubstituted groups: amino, C1-C6 aliphatic hydrocarbon, C3-C7 cyclic aliphatic hydrocarbon, C1-C6 alkoxy, C2-C7 carbalkoxy, C1-C4 acyloxy, C6-C20 aryl, or 5 to 7 members heterocyclic or benzoheterocyclic thereof; or R5 and R6 form the group of formula (IV). The compounds of present invention are cheap, safe and effective because that they mostly come from traditional Chinese medicines and have better anti-HCV effects and lighter side effects.

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