| 专利名称 | 2-ARYLBENZOFURAN-7-FORMAMIDE COMPOUNDS, PREPARATION METHOD AND USE THEREOF | 申请号 | EP20130746724 | 专利类型 | EP | 公开（公告）号 | EP2813495(B1) | 公开（授权）日 | 2016.09.28 | 申请（专利权）人 | 中国科学院上海药物研究所 | 发明（设计）人 | YANG, CHUNHAO;MIAO, ZEHONG;DING, JIAN;WANG, MENG;HE, JINXUE;TAN, CUN;CHEN, YI | 主分类号 | C07D307/81 | IPC主分类号 | C07D307/81;A61P29/00;A61P35/00;C07D405/04;C07D405/12 | 专利有效期 | 2-ARYLBENZOFURAN-7-FORMAMIDE COMPOUNDS, PREPARATION METHOD AND USE THEREOF 至2-ARYLBENZOFURAN-7-FORMAMIDE COMPOUNDS, PREPARATION METHOD AND USE THEREOF | 法律状态 | 说明书摘要 | Provided in the present invention are a 2-arylbenzofuran-7-formamide compound as shown in general formula I or a pharmacologically or physiologically acceptable salt thereof, a preparation method thereof and use thereof in preparing anti-tumour drugs, wherein R 1 and R 2 are each independently hydrogen, straight or branched chained C 1 -C 4 alkyl, C 3 -C 4 cycloalkyl or saturated 5- or 6-membered heterocyclyl containing oxygen or nitrogen; or R 1 and R 2 together with N form an unsubstituted or substituted saturated 5- or 6-membered heterocyclyl containing at least one heteroatom, wherein the heteroatom is O, N and S, the substituent is a methyl on N; R 3 is a hydrogen atom or a chlorine atom; R 4 is a hydrogen atom or a fluorine atom; X is CH, CF or N; and Y is CH, CF or N. |
1、源头对接，价格透明
2、平台验证，实名审核
3、合同监控，代办手续
4、专员跟进，交易保障