Alpha-amino-N-substituted amides, pharmaceutical composition containing them and uses thereof

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专利名称 Alpha-amino-N-substituted amides, pharmaceutical composition containing them and uses thereof 申请号 US20080747485 专利类型 US 公开(公告)号 US8470763(B2) 公开(授权)日 2013.06.25 申请(专利权)人 中国科学院上海药物研究所 发明(设计)人 NAN FAJUNLI JIADING JIANLIU GANGXIE CHUANMINGMIAO ZEHONGTAI WANY 主分类号 C07D345/00 IPC主分类号 C07D345/00 专利有效期 Alpha-amino-N-substituted amides, pharmaceutical composition containing them and uses thereof 至Alpha-amino-N-substituted amides, pharmaceutical composition containing them and uses thereof 法律状态 说明书摘要 Disclosed are a series of alpha-amino-N-substituted amide compounds having a structure of the following formula, the pharmaceutically acceptable salts thereof, and the pharmaceutical composition comprising the same. The alpha-amino-N-substituted amide compounds or the pharmaceutically acceptable salts thereof according to the present invention have anti-tumor and/or anti-cancer activities in vivo and in vitro, can effectively depress the growth of various tumor cells and/or cancer cells, and thus can be used in preparing drugs for treating tumors and/or cancers.

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