| 专利名称 | Rapamycin carbonic ester analogues, pharmaceutical compositions, preparations and uses thereof | 申请号 | US200913119700 | 专利类型 | US | 公开（公告）号 | US8455510(B2) | 公开（授权）日 | 2013.06.04 | 申请（专利权）人 | 中国科学院上海药物研究所 | 发明（设计）人 | NAN FAJUNDING JIANZUO JIANPINGYU LINQIANMENG LINGHUAZHANG YANGMINGYANG NAGU MI | 主分类号 | C07D498/18 | IPC主分类号 | C07D498/18;A61K31/436;A61P35/00 | 专利有效期 | Rapamycin carbonic ester analogues, pharmaceutical compositions, preparations and uses thereof 至Rapamycin carbonic ester analogues, pharmaceutical compositions, preparations and uses thereof | 法律状态 | 说明书摘要 | Rapalogs of formula I, pharmaceutically acceptable salts, pharmaceutical compositions, and preparation methods and uses thereof. The rapalogs have the structure of formula I and can be used as an anti-tumor medicament. Comparing with rapamycin, the rapalogs of the present invention exhibit enhanced water solubility, and improved pharmacological and pharmacokinetic properties by introducing a hydrophilic and polar group such as a hydroxyl. |
1、源头对接，价格透明
2、平台验证，实名审核
3、合同监控，代办手续
4、专员跟进，交易保障