| 专利名称 | THE USE OF SUCCINATE DERIVATIVE ESTERS FOR THE TREATMENT OF DEMENTIA | 申请号 | EP20030782083 | 专利类型 | EP | 公开（公告）号 | EP1582209(B1) | 公开（授权）日 | 2012.09.19 | 申请（专利权）人 | 中国科学院上海药物研究所 | 发明（设计）人 | ZHANG JIANJUNSHI JIANGONGWANG YAFANGZHANG DANGAO MEIYANG YONGCHUNHUANG SHENGYAN | 主分类号 | A61K31/222 | IPC主分类号 | A61K31/222;A61K31/194;A61K31/7012;A61K31/7028;A61P25/28 | 专利有效期 | THE USE OF SUCCINATE DERIVATIVE ESTERS FOR THE TREATMENT OF DEMENTIA 至THE USE OF SUCCINATE DERIVATIVE ESTERS FOR THE TREATMENT OF DEMENTIA | 法律状态 | 说明书摘要 | The use of extract form Wangla (coeloglossum viride (L) Hartm. Var. Bracteatum (Willd.) Richter), succinate derivative esters, and a derivative and pharmaceutical acceptable salts thereof, for the manufacture of a pharmaceutical preparation for the treatment of dementia, particularly for the treatment of Alzheimer'' disease and Vascular dementia. Through Animal experiment, it has been demonstrated that, succinate derivative esters can improve learning and memory ability in dementia rats induced by scopolamine and cyclohexenyl imine; improve learning and memory ability in dementia rats induced by beta-amyloid; improve learning and memory ability in dementia rats induced by permanent ligation of bilateral carotid; and improve memory ability of normal animals. It has the advantage of high activity, low toxicity and no inhibition to cholinesterase. |
1、源头对接，价格透明
2、平台验证，实名审核
3、合同监控，代办手续
4、专员跟进，交易保障