| 专利名称 | Paliperidone double-layered osmotic pump controlled release tablet and preparation method thereof | 申请号 | GB20120011226 | 专利类型 | GB | 公开（公告）号 | GB201211226(D0) | 公开（授权）日 | 2012.08.08 | 申请（专利权）人 | 中国科学院上海药物研究所 | 发明（设计）人 | 主分类号 | IPC主分类号 | 专利有效期 | Paliperidone double-layered osmotic pump controlled release tablet and preparation method thereof 至Paliperidone double-layered osmotic pump controlled release tablet and preparation method thereof | 法律状态 | 说明书摘要 | A paliperidone double-layered osmotic pump controlled release tablet and the preparation method thereof are disclosed. The double-layered osmotic pump controlled release tablet comprises rigid membrane, push layer, drug layer, separating layer and aesthetic coating is disclosed. The rigid membrane contains semi-permeable polymer, hole-forming agent and/or plasticizer and has one or more delivery orifices on one end. The push layer comprises expanding material, permeation-promoter, binder, colorant and lubricant. The drug layer contains pharmaceutical active component, hydrophilic polymer carrier, permeation-promoter, colorant, lubricant and antistatic agent. The separating layer is between the inner surface of the rigid membrane and core comprised of drug layer and push layer and contains hydrophilic polymer. The paliperidone double-layered osmotic pump controlled release tablet shows increased release at initial stage and keeps constant release at late stage. |
1、源头对接，价格透明
2、平台验证，实名审核
3、合同监控，代办手续
4、专员跟进，交易保障