| 专利名称 | Method of imaging with fluorescent microspheres | 申请号 | US20070441894 | 专利类型 | US | 公开（公告）号 | US8460638(B2) | 公开（授权）日 | 2013.06.11 | 申请（专利权）人 | 中国科学院过程工程研究所 | 发明（设计）人 | MA GUANGHUISU ZHIGUOWEI WEIWANG LIANYANWEI QIAN | 主分类号 | A61B5/00 | IPC主分类号 | A61B5/00 | 专利有效期 | Method of imaging with fluorescent microspheres 至Method of imaging with fluorescent microspheres | 法律状态 | 说明书摘要 | A method of fluorescence imaging is disclosed that uses a non-labeled fluorescent microsphere comprising a primary amine polymer, wherein the microsphere does not contain an additional fluorescent substance, and wherein at least one primary amine group in the primary amine polymer has the structure of -N=R-, in which R is a residue after the reaction of an aldehyde-type cross-linking substance, and the other primary amine groups have the structure of -NH2. The fluorescence color of the microspheres can be adjusted by selecting different aldehyde-type cross-linking substances or combinations, and the fluorescence intensity of the microspheres can be controlled not only by the addition of the aldehyde-type cross-linking substances and the time of the cross-linking reaction, but also by adjusting the diameters of the microspheres. |
1、源头对接，价格透明
2、平台验证，实名审核
3、合同监控，代办手续
4、专员跟进，交易保障